(943) Hemodynamic Effects of Intra-Aortic Balloon Pump as a Bridge to Durable Left Ventricular Assist Device

PurposeIntra-aortic balloon pump (IABP) therapy is often used to bridge patients durable left ventricular assist device (LVAD). We examined the hemodynamic changes following IABP insertion in cardiogenic shock requiring LVAD therapy.MethodsWe performed a retrospective observational study of receiving an as from 2015-2021. Hemodynamic metrics including right atrial pressure (RAP), pulmonary artery pressures (PAP), mixed venous oxygen saturation (SvO2), and cardiac output/indices (CO/CI) were collected at 1-hour, 24-hours, 48-hours post-IABP well day LVAD. Post-IABP measures compared pre-IABP state. Heart failure-related labs drawn prior 48 hours post-IABP. All p values < 0.05 considered significant.ResultsA total 104 analyzed. Mean (SD) age was 55.8 (11.9) years old median (IQR) days on support 4.5 (3.1). Improvement RAP PAP noted 24- placement placement. SvO2 CO/CI higher all time points (Figure). with exception sodium improved 48-hour interval (Table).ConclusionIABP improves profiles bridged early 1-hour post-placement persists until implantation. IABPs can serve effective platform selected Future research should be focused identification predictors response advanced heart failure patients. Intra-aortic therapy. significant. A (Table).